THE ANTI-APOPTOTIC ROLE OF NEUROGLOBIN

The Anti-Apoptotic Role of Neuroglobin

The small heme-protein neuroglobin is expressed at high concentrations in certain brain neurons and in the rod cells of the retina.This paper reviews the many studies which have recently identified a protective role for neuroglobin, in a wide range of situations involving apoptotic cell death.The origins of this protective mechanism are discussed G

read more



Airway Epithelial Inflammation In Vitro Augments the Rescue of Mutant CFTR by Current CFTR Modulator Therapies

In cystic fibrosis (CF), defective biogenesis and activity of the cystic fibrosis transmembrane conductance regulator (CFTR) leads to airway dehydration and impaired mucociliary clearance, resulting in chronic airway infection and inflammation.The most common CFTR mutation, F508del, results in a processing defect in which the protein is retained in

read more